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Twice this week, I have watched an elderly individual, fade into the busy life in which we all live. One man just needed Panadol for his wife but the shop assistant simply said it’s in ‘6’. But he struggled to navigate the supermarket and as I watched him go in the wrong direction, I left all my groceries and took him where he needed to go. Today, I watched an elderly man struggle in the heat, who had obviously had a fall with a huge scrape and blood on his leg. He walked past people in the cafe, while he slowly made his way to his car. Not one person stopped. Or looked. Or acknowledged him. I took him to his car and checked he was ok. He told me he had a fall and wasn’t sure how the air con worked in his car so he just didn’t use it. I sat with him, until his air con kicked in and heard him talk about the old frail body that he is in, that fails him now, every single day.When you see an elderly person walking down the street, searching in the supermarket or struggling to their car, take a minute out of your busy schedule and ask them if they need a hand. Think about your grand parents and your parents and how pissed you would be if someone didn’t stop to help them. But more, think of them as you.Once upon a time they were you. They were busy, they had work, they had children, they were able…. Today, they are just in an older body that is not going as fast as it used to and this busy life is confusing. They deserve our utmost respect and consideration. One day it will be you, it will be us. I wish more people gave a sh*t about them and acknowledged them for their admirable existence and geez I hope someday, not that far away, someone does it for me.Credit: Adele Barbaro
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Could a potential cure for Type-1 Diabetes be on the horizon? Researchers have been studying Zimislecel, a promising new treatment that’s showing incredible results in combatting this chronic disease. In this video, we’ll dive into the latest findings mean for those affected and what the future might hold. Is a Type-1 Diabetes cure finally within our grasp?
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Clinical Trial Tests Cell Therapy to Cure People with Type 1 Diabetes 7/14/2025 · Research Vertex is recruiting participants for its zimislecel (VX-880) cell therapy trial. Early study results show promise that zimislecel may be the first functional cure for type 1 diabetes. Trial status: Recruiting Clinical Trials Identifier: NCT04786262
Trial name: A Safety, Tolerability, and Efficacy Study of VX-880 in Participants with Type 1 Diabetes Diabetes type: Adults 18-65 years of age with type 1 diabetes
Trial sponsor: Vertex Pharmaceuticals
This clinical trial is testing zimislecel (VX-880), the first fully differentiated cell-derived islet cell therapy for type 1 diabetes. Early study results so far are promising, with 12 participants no longer needing daily insulin after one year of therapy. Though immunosuppressants are required to prevent the body’s immune system from attacking and destroying the new cells (similar to when someone receives an organ transplant), research so far indicates that zimislecel could be the first functional cure for type 1 diabetes.
This clinical trial is unique in that it’s a combination phase 1, 2, and 3 trial. That means participants are being recruited to receive the therapy for the first time, as well as following people who have been in the study for years to see how zimislecel is working longer term.
You may be eligible to participate if you:
- Are 18-65 years old Have been diagnosed with type 1 diabetes for at least five years
- Have had at least two episodes of documented severe hypoglycemia in the past year
- Are on a stable diabetes treatment plan
- Have used a continuous glucose monitor (CGM) consistently for at least three months prior to screening for the trial, and are willing to use the CGM during the trial
- Have not had any prior islet cell transplants, organ transplants, or cell therapy
This trial is currently recruiting in 29 locations worldwide, including the U.S., Canada, France, Germany, the Netherlands, Norway, Switzerland, and more. Learn more about this study here or contact the Vertex study team at medicalinfo@vrtx.com or call (+)1-617-341-6777.
https://diatribe.org/diabetes-research/clinical-trial-tests-cell-therapy-cure-people-type-1-diabetes